As diagrammed in Fig. Genes are made of DNA, a nucleic acid. Structure of Nucleic Acids. THE NUCLEIC ACIDS MEENAKSHY SUDEEP 2. See our Privacy Policy and User Agreement for details. Understand how Coenzyme-A is used to transfer acyl groups. Clipping is a handy way to collect important slides you want to go back to later. The nucleus contains the cell’s DNA, which makes up the genome. NUCLEIC ACIDS AND THEIR. The diseases are: 1. Disorders of nucleic acid metabolism- hyperuricemia,hypouricemia,gout Additionally, parts of the nucleotides or nucleobases can be salvaged to recreate … 2. In other meaning, this disease is the severe scarring of the liver and the poor liver function will show at the terminal stages of the chronic liver disease because it's often caused by the long-term exposure to the toxin such as alcohol or vital infection. Objectives By the end of lecture the student should: Define nucleic acids. After reading this article you will learn about 1. Nucleotide Metabolism: An Introduction is a textbook exclusively focusing on the study of the aspects of nucleotide metabolism. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Understand how ATP is formed from ADP and inorganic phosphate (P i), and vice versa. Nucleic acid - Nucleic acid - Nucleic acid metabolism: Replication, repair, and recombination—the three main processes of DNA metabolism—are carried out by specialized machinery within the cell. Von Gierke’s Disease 6. Nucleic Acids By: Gianna, Alex, and Gabriel THE END Body parts or plant parts where Nucleic Acids Can be found Human They are found in human DNA and RNA Polymers Plant Deoxyribonucleic Acid Also known as DNA holds the information on all the characteristics of your body there are The text is divided in two parts. Catabolism of Nucleosides. The nucleus is surrounded by a nuclear envelope, two membrane bilayers Molecules come into and out of the nucleus through nuclear pores The inside of the nucleus is called the nucleoplasm. Nucleotides and Nucleic Acids Chapter 8 Lehninger 5th ed. "Dictionary" of amino acid code words in mRNAs. Illustrate structure of nucleotides. Nucleic acids are the most important macromolecules for the continuity of life.They carry the genetic blueprint of a cell and carry instructions for the functioning of the cell. ADVERTISEMENTS: The following points highlight the six major diseases caused due to errors in nucleic acid metabolism. 1 Chapter 15 Lecture Notes: Metabolism Educational Goals 1. Nucleic acid is an important class of macromolecules found in all cells and viruses. Clipping is a handy way to collect important slides you want to go back to later. If you continue browsing the site, you agree to the use of cookies on this website. See our User Agreement and Privacy Policy. Nucleic Acid Chemistry Dr: Hussein abdelaziz. A single nucleotide is made up of three components: a nitrogen-containing base, a five-carbon sugar (pentose), and at least one phosphate group With all three joined, a nucleotide is also termed a “nucleoside phosphate”. Understand the roles of the NAD +/NADH and FAD/FADH 2 Looks like you’ve clipped this slide to already. Let us make an in-depth study of the nucleic acid metabolism. Lesch-Nyhan Syndrome 2. Nucleic Acid Metabolism Nucleotides Essential for all cells Carriers of activated intermediates in carbohydrate, lipids and proteins CoA FAD NAD NADP – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3d0ba4-YWQ5N NUCLEIC ACID • Nucleic acid are polymers that consist of nucleotide residues. Nucleic Acid Analysis. The nucleus contains the cell’s DNA, which makes up the genome. • most nucleic acids in the cell are associated with protein • dietary nucleoprotein is degraded by pancreatic enzymes and tissue nucleoprotein by lysosomal enzymes • after dissociation of the protein and nucleic acid, the protein is metabolized like any other protein • the nucleic acids are hydrolyzed randomly by nucleases to yield a Topic : Nucleic acids Errors that creep in during replication or because of damage after replication must be repaired. who discovered nucleic acids in 1871. Nucleic acids are the biomolecules that are essential for every form of life present on the earth. Metabolism of nucleic acids (4) Antagonists of deoxy- nucleotide biosynthesis (4) Antagonists of deoxy- nucleotide biosynthesis 3. nucleic acid ppt 1. Nucleic acids and nucleotides methabolism, Ivano-Frankivsk National Medical University (IFNMU), Biomolecular ligand-receptor-binding-studies-theory, No public clipboards found for this slide. HISTORIC RESUME Friedrich Miescher in 1869 • Isolated what he called nuclein from the nuclei of pus cells • Nuclein was shown to have acidic properties, hence it became called nucleic acid 3. 3. Friedrich Miescher Lesch-Nyhan Syndrome: a. Thus, to make nucleic acids for cell proliferation purposes, cells have to upregulate both energy metabolism and the nucleotide biosynthetic pathways. Hypouricemia 5. In most cases, codons that specify the same amino acid differ only at the third base. METABOLISM Naresh panigrahi Gitam university Nucleic Acid. ( e.g RNA ) are synthesized and degraded nitrogenous base replication must repaired... Nucleotide synthesis is ananabolic mechanism generally involving the loss of liver cells and nucleic acid metabolism ppt slideshare complex. Nucleotides, one of the NAD +/NADH and FAD/FADH 2 Let us an. Nucleic acids ( DNA ) encodes the information the cell ’ s,... 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